Sunday, November 26, 2017

Creative BioMart to Expand Its Protein Glycosylation Labeling Service Capacity to Meet Rising Demands

Creative BioMart, a global leader in the supply of high quality protein products and efficient protein manufacturing techniques, today announced a major expansion of its Protein Glycosylation Labeling Service capacities as a response to rising customer needs and market demands for characterizing glycan structure and monitoring glycan profiles.

With years of experience accumulated, Creative BioMart provides accurate solutions for characterizing glycan structure and monitoring glycan profiles using mAb-Glyco Chip technology, LC/MS, liquid chromatography systems, and electrophoresis. Services in Creative BioMart include: Annotate N-linked glycosylation, Annotate O-linked glycosylation, Annotate C-linked glycosylation, Annotate glycationn, Glycan staining or labeling, Glycoprotein purification or enrichment and Glycoproteome and Glycome Analysis by Mass Spectrometry.

As Lectins can be used to detect and analyze glycoprotein function, Creative BioMart also provides services utilizing lectins, which include Glycoprotein identification, Glycoprotein purification/enrichment, Characterization of cell surface glycoconjugates, Glycosylation mutant generation, as well as Gtf and glycosidase activity analysis.

With the customers needs for Protein Glycosylation Labeling increased, we are quite pleased to develop more qualified offerings concerning this with our current services quality assured. We must work hard for early results. Guaranteed by our advanced techniques, we do believe the day is no faraway to come. Commented the chief marketing staff in Creative BioMart.

To know more detailed information about Protein Glycosylation Labeling Service in Creative BioMart, you can visit http://www.creativebiomart.net/Protein-Glycosylation-Labeling-Service.htm.

About Creative BioMart
Starting from a small supplier of proteins and enzymes for academic institutes and biotech companies, Creative BioMart has always been focusing on developing high quality protein products including recombinant proteins, GMP proteins, native proteins, etc. and efficient protein manufacturing techniques. Over the past decade, our products and services are proved to have served our customers well and our brand has become one of the most trustworthy in the market.

Monday, October 23, 2017

Engineered Proteins Created to Treat Obesity

According to the material provided by American Association for the Advancement of Science, Scientists here have created engineered proteins that brought down body weight, bloodstream insulin, and cholesterol levels in obese mice, rats and primates. These findings, to some extent, pave the way for earnestly required alternatives to bariatric surgery for treating obesity in humans-the rates of which have almost tripled worldwide since 1975.

In view of the perception that obese mice, rats, and humans all had raised serum concentrations of a protein named GDF15 in contrast with learn controls, Yumei Xiong and partners set out to create treatments got from the molecule. In various mouse models of diet-induced and genetic obesity, conveyance of the GDF15 gene reduced body weights, food intake, and serum insulin levels in the animals.

Since GDF15 has a short plasma half-life and is hard to deliver in substantial quantities, the researchers produced two distinctive fusion proteins that were more stable in the circulation and prompted higher yields. Both fusion proteins adequately diminished body weights for obese mice and cynomolgus monkeys.

What’s more interesting is that, Xiong, together with her colleagues, additionally demonstrated that the GDF15 regimen changed food preferences in mice—driving the animals to pick lower calorie chow when offered a decision between standard food and an additional condensed-milk diet.

The authors established that GDF15 enacted a population of nerve cells called AP neurons that make up a portion of the gut-brain axis, yet take not of that further investigations to identify the protein’s cellular receptor are required as potential therapeutics advance toward the clinic.

As a quality protein products supplier, Creative  BioMart not only provides GDF15 proteins, but also GDF11 proteins, and other protein products and protein-related services to assist scientists with their research.